1.5.7. Генетика

Regularities of the processes of transport and deposition of soil material by water flows small depth The main objective of this work by the example of soddy-podzolic soil of different degree of wash off quantitatively assess the ability of small depth flows at the system level «flow-soil» to transfer certain mass of soil material. Determination of quantities transfer and deposition of soddy-podzolic soil of different degree of wash off spend on a large erosive tray. In the experiments was determined by the following indicators: the average velocity of flow and turbidity of water, the radius of the transported and deposited in the stream bed of aggregates and other. These indicators are used for verification of the theoretical equation transporting capacity.  

Application of the European soil standards in the territory of Azerbaijan At present the integration to the European and international structures goes on in many directions, including scientific. Against a background of globalization it is fundamentally important to form an adequate soil-information space which would ensure progressive international cooperation in the field of soil science. As is known, the new digital soil database of Mediterranean and Caucasus Countries’ territory in the format of the soil geographical information system of the European Union (EU) is being prepared within the program for the Extension of the European Soil Database (ESDB). These researches intend to create the Soil Geographical Database of Eurasia at scale 1 : 1, 000, 000 as a part of the European Soil Information System (EUSIS). The current stage of the Azerbaijan soil resources inventory on supranational level is closely linked with the processes of adaptation of the country to the conditions of new geopolitical realities. It is of fundamental importance to preserve and develop the national scientific and practical traditions and their harmonious integration with the EU soil inventory. Taking into consideration the urgency of the problem, we have made researches in order to create the digital data base of the soils of the Republic of Azerbaijan. The digital soil map of Azerbaijan has been prepared in a scale of 1:1000000 using modern geoinformation technologies and taking into account the ESDB requirements. During the analysis of soil database of Azerbaijan, some difficulties that impede the integration process to the ESDB were revealed. Generally, the work that has been done brought to a conclusion that the knowledge available on soils of Azerbaijan makes the integration to the EU soil-geographic data base possible.  

Experience to improve the fertility of soil in nurseries Eastern Transbaikalia Pak Larisa Nikolaevna, Bobrinev Viktor Petrovich The results of studies on the establishment of a forest nursery of Eastern Transbaikalia effective crop rotation, allowing to preserve the fertility of the soil, grow trees planting material in a shorter period and to reduce the cost of cultivation more than doubled.

Features photosynthesizing activity in needles Picea ajanensis and Picea Smithiana in the town forests in Ussuriisk Titova M.S., Rozlomiy N.G. The content and the ratio of exchange photosynthetic pigments in the needles of Picea ajanensis and Picea Smithiana were investigated in the town forests in Ussuriisk . It is established that the amount of photosynthetic pigments of introduce species is inferior to the local species. These data extend the idea of the pigment complex of introduced coniferous species and can be used to diagnose the state of photosynthetic apparatus.

The induction of chromosomal aberrations by etoposide in Cyclops kolensis и Cyclops insignis (Copepoda, Crustacea) A.K. Grishanin, G.E.Grishanin The frequency of chromosome aberrations in the embryonic cells of Cyclops kolensis and Cyclops insignis was determined when cyclops embryos were treated with Etoposide . A reduction in the frequency of chromosome aberrations (CA) in somatic cells lines Cyclops kolensis after chromatin diminution was installed. It's shown that chromosome aberrations frequency of Cyclops insignis at appropriate stages of embryogenesis due to the impact of Etoposide solution of the same concentration did not change. The significant differences in the CA frequencies of somatic line cells of Cyclops kolensis when embryos were exposed in increasing concentrations of Etoposide solutions  out.

Architectural and morphometric analysis of tree species The growth is described as variations of bine-gemma complex. New marks for characteristic of the growth of crown for different types of plants were performed the mark of participation of gemmas, multiple number of augmentation, mart of bines growth leading. This method is different plants on the perspective types into introduction future nature.

Age and tissue-specific features of the peroxide modification of proteins against the background of emotional-painful stress and preliminary introduction of а-tocopherol Investigated age differences and the level of peroxidation of proteins of male white rats when emotional-painful stress and the introduction of α-tocopherol. The changes in the intensity of peroxide degradation of proteins in various tissues, depending on the age of the animal. Shown as a protective and prooxidant effect of α-tocopherol, depending on the age and the tissue under examination.  

The effect of humic substances and pesticides on the yield of spring wheat The paper presents the research on the effect of humic substances in tank mixtures with pesticides on the structure of the crop, the development of root rot, grain yield and quality of spring wheat.  

Disorders of cellular and humoral immunity ulcer diseases The article deals with contemporary ideas on the state of immunological reactivity under ulcer disease. The role of immune disturbances in the development of clinical manifestations of ulcer disease is shown. Interrelations of different links of the immune system, correlations between specific immunity and natural protection of the organism are considered. Found that patients observed a variety of disorders immunological reactivity. Violations of the immunological reactivity observed in the acute stage and remain in remission.  

The levels of UV-induced mutagenesis change in case of mutations in chromatin-remodeling proteins encoding genes are combined with the rad54 mutation in yeast Saccharomyces cerevisiae Yeast Saccharomyces cerevisiae DOT1, HSM6 and ASF1 genes encode crucial protein chromatin modifiers. We studied the effects of combining dot1, hsm6 and asf1 mutations with rad54 mutation. It’s demonstrated that the enormous increase of UV-induced mutagenesis is representative for dot1rad54, hsm6rad54 and asf1rad54 double mutants. Simultaneously the levels of survival of these double mutants change under the UV light action.

Morphological and physiological parameters of erythrocytes in oxidative stress at different stages of ontogenesis The results indicate the age-related deviations from physiological level of the prevailing number of the investigated morphological and physiological parameters of peripheral erythrocytes functional status, indicating the lack of these indicators stability in the late ontogenesis, significant defects of the gas transmission function of red blood cells, especially presented when inhale rats with hydrogen sulfide gas.  

The effect of Mexidol on clinical and immunological status of patients with chronic obstructive pulmonary disease The assessment of efficiency of meksidol therapy on clinical and immunological status has been made for patients with chronic obstructive pulmonary disease (COPD), the acceptability of physical loads, quality of life and probability of survival of patients with COPD being cousidered against the background of mexidol treatment. It has been established that the use of this preparation in a complex therapy for COPD patients is accompanied by positive dynamics of respiratory symptoms and improves the quality of life of patients. Patients with COPD have a depression of absorbency of neutrophil phagocytics capacity and increasing its metabolic activity with the formation of reactive oxygen species, the probability of a 4 year survival in patients with COPD.  

Research on the influence of endogenous bioregulators, isolated from blood serum and bones of mammals, on the regeneration of amphibian limbs The purpose of this study was to investigate the effect of bioregulators (BR) on anurans limb regeneration and to maintain the viability of the tissues of the developing salamanders regenerate in vitro. During this work it was found that the ability of Xenopus laevis to regenerate hindlimb in metamorphosis stage depends on the level of amputation, while stimulating regeneration by BR isolated from blood serum, decreases when the regenerative capacity increases. BR from serum had a pronounced effect on the regeneration of Xenopus laevis hindlimb in vivo when amputation was in the proximal region. BR from bone and BR from serum had a protective effect on the condition of the tissue regenerated limb of the newt Pleurodeles waltl provided by cultivation in vitro.  

Investigation of thermal resistance and antagonistic properties of the yeast Saccharomyces cerevisiae Using antagonistic properties of some bacteria to inhibit other (pathogenic) has been studied for many years, while little attention was paid to study such properties in yeast. The yeast metabolites and yeast cells action on gram-negative and gram-positive microorganisms was different. Live yeast cells were the most antagonistically active against gram-positive microorganisms and their metabolites - in relation to gram-negative.  

Regularities of formation and erosion processes during spring snowmelt on the territory of agrolandscape and their impact on the quality of river water Analysis of the results four years of research of the snowmelt runoff formation and soil loss on the catchment area of the small river Lubozhikha showed that surface runoff and soil washout has an influence not only on the intensity of erosion processes, but also on the chemical composition of river waters.  

The epithelial-mesenchymal transition is one of the sources of the emergence of new cancer stem cells in response to cancer chemotherapy. The initiation of this process depends on a number of transcription factors - Snail, Twist, Zeb, which regulate the activity of genes, involved in cellular phenotype and inter-tissue interactions. In turn, Snail, Twist, Zeb are targets for the regulation of the nuclear factor kappa bi (NF-kappaB) cascade, one of the leading signaling pathways of cell adaptation and defence both under normal conditions and in the pathogenesis of a wide range of diseases, including various oncologies. This review study examines the interaction of NF-kappaB with genes regulating epithelial-mesenchymal transition in cancer cells. The mechanisms of information transfer and the activation pathways of the NF-kappaB signaling pathway and the regulatory network of transcription factors of the epithelial-mesenchymal transition are considered. Data on the factors of initiation of epithelial-mesenchymal transition with the NF-kappaB participation are presented. Roles of specific components in NF-kappaB signaling pathway are presented separately in this trigger, as well as cooperation with other signaling cascades involved in the tumors development. It also demonstrates the usage of various pharmacological, including protein, inhibitors of the NF-kappaB cascade to prevent EMT triggering. In conclusion, the facts about the regulation of NF-kappaB activity due to the reverse loop formed by the products of the target genes of the Snail, Twist, Zeb factors are presented. This work is of interest to specialists in the field of cell biology, human genetics and molecular oncology

The accumulation of toxicants in the body of bees and honey in the conditions of ecologically crisis areas of the Republic of Tatarstan The article is devoted to the study of contamination of honey bees and honey toxicants in oil-producing regions of the Republic of Tatarstan. The results of the accumulation of a number of toxicants in the body of bees and honey.

Monitoring of mushrooms Agaricus bisporus (J. Lge) Imbach: diagnostics and prevention of diseases We conducted research and experiments and we determined that the mushrooms (Agaricus bisporus (J. Lge) Imbach) infected with bacteria, viruses, microscopic fungi. We recommend prevention activities to fight infections.