03.03.01 Физиология

Behavioral effects of female sex hormones of different nature of the immobilized male white rats Frolova Galina Aleksandrovna, Bogdanova Svetlana Aleksandrovna Found that the sensitivity of male white rats to immobilization stress (10 days of 2 hours) is directly dependent on baseline activity of the animals. Natural female sex steroid estrone (estrone, 1.0 mg/kg, 10 days) caused an inhibition of locomotor and exploratory activity in stressed rats is not dependent on the initial level of activity. Synthetic analogue of the female sex hormone origin of non-steroidal (sinestrol, 0.8 mg/kg, 10 days) in low and intermediate level of stressed rats acts as a stress-limiting factor, high-level direction of impact of sinestrolom coincides with the effects of estrone.

Age and tissue-specific features of the peroxide modification of proteins against the background of emotional-painful stress and preliminary introduction of а-tocopherol Investigated age differences and the level of peroxidation of proteins of male white rats when emotional-painful stress and the introduction of α-tocopherol. The changes in the intensity of peroxide degradation of proteins in various tissues, depending on the age of the animal. Shown as a protective and prooxidant effect of α-tocopherol, depending on the age and the tissue under examination.  

Morphological and physiological parameters of erythrocytes in oxidative stress at different stages of ontogenesis The results indicate the age-related deviations from physiological level of the prevailing number of the investigated morphological and physiological parameters of peripheral erythrocytes functional status, indicating the lack of these indicators stability in the late ontogenesis, significant defects of the gas transmission function of red blood cells, especially presented when inhale rats with hydrogen sulfide gas.  

Research on the influence of endogenous bioregulators, isolated from blood serum and bones of mammals, on the regeneration of amphibian limbs The purpose of this study was to investigate the effect of bioregulators (BR) on anurans limb regeneration and to maintain the viability of the tissues of the developing salamanders regenerate in vitro. During this work it was found that the ability of Xenopus laevis to regenerate hindlimb in metamorphosis stage depends on the level of amputation, while stimulating regeneration by BR isolated from blood serum, decreases when the regenerative capacity increases. BR from serum had a pronounced effect on the regeneration of Xenopus laevis hindlimb in vivo when amputation was in the proximal region. BR from bone and BR from serum had a protective effect on the condition of the tissue regenerated limb of the newt Pleurodeles waltl provided by cultivation in vitro.  

Formation of the liver in amphibian larval period on the example of the green toad (Bufo Viridis Laurenti, 1768) Describes the morpho-physiological characteristics of the emerging liver in larvae of the green toad (Bufo viridis Laurenti, 1768). Identified that studied the body performs the function of blood during larval development period. In the liver are formed elements of the blood of all lines. Describes he specifics of the organization and morphological changes of the body from developing larvae. There are some pathological changes in the liver and formed elements of blood.

Features of action of weak low-frequency alternating magnetic field on the intensity of division planarian Dugesia tigrina at static magnetic field with "zero" and geomagnetic values It have been shown that exposure of the planarians to low-frequency alternating magnetic field (frequency of 3,7 Hz, the amplitude of 40 nT, exposure 4 h) in combination with a static magnetic field collinear with the induction of 42 mT promoted its division. On other hand compensation of the static magnetic field (induction £ 0,1 mT) by means of alternating magnetic field resulted in the opposite directional inhibitory effect consisted of reduction of the number of divisions of planarians.

The Influence of the Spatial Variability on the Goal-Directed Behavior Organization Serkova V. V., Nikolskaya K. A. The influence of the spatial variability on the goal-directed behavior organization in adult mice line F1 from DBA/2J and C57BL/6J was studied. It has been found that sudden change of initial structure of the maze during the moment of imprinting of spatial information has negatively affected on possibility to form the adaptive behavior in accordance with the offered task conditions. It is assumed that the constancy of the initial spatial information can be an system factor which together with the other will ensure the success of the cognitive process.

Behavioral effects of female sex hormones of different nature of the immobilized male white rats Frolova Galina Aleksandrovna, Bogdanova Svetlana Aleksandrovna Found that the sensitivity of male white rats to immobilization stress (10 days of 2 hours) is directly dependent on baseline activity of the animals. Natural female sex steroid estrone (estrone, 1.0 mg/kg, 10 days) caused an inhibition of locomotor and exploratory activity in stressed rats is not dependent on the initial level of activity. Synthetic analogue of the female sex hormone origin of non-steroidal (sinestrol, 0.8 mg/kg, 10 days) in low and intermediate level of stressed rats acts as a stress-limiting factor, high-level direction of impact of sinestrolom coincides with the effects of estrone.

Age and tissue-specific features of the peroxide modification of proteins against the background of emotional-painful stress and preliminary introduction of а-tocopherol Investigated age differences and the level of peroxidation of proteins of male white rats when emotional-painful stress and the introduction of α-tocopherol. The changes in the intensity of peroxide degradation of proteins in various tissues, depending on the age of the animal. Shown as a protective and prooxidant effect of α-tocopherol, depending on the age and the tissue under examination.  

Morphological and physiological parameters of erythrocytes in oxidative stress at different stages of ontogenesis The results indicate the age-related deviations from physiological level of the prevailing number of the investigated morphological and physiological parameters of peripheral erythrocytes functional status, indicating the lack of these indicators stability in the late ontogenesis, significant defects of the gas transmission function of red blood cells, especially presented when inhale rats with hydrogen sulfide gas.  

Research on the influence of endogenous bioregulators, isolated from blood serum and bones of mammals, on the regeneration of amphibian limbs The purpose of this study was to investigate the effect of bioregulators (BR) on anurans limb regeneration and to maintain the viability of the tissues of the developing salamanders regenerate in vitro. During this work it was found that the ability of Xenopus laevis to regenerate hindlimb in metamorphosis stage depends on the level of amputation, while stimulating regeneration by BR isolated from blood serum, decreases when the regenerative capacity increases. BR from serum had a pronounced effect on the regeneration of Xenopus laevis hindlimb in vivo when amputation was in the proximal region. BR from bone and BR from serum had a protective effect on the condition of the tissue regenerated limb of the newt Pleurodeles waltl provided by cultivation in vitro.  

Formation of the liver in amphibian larval period on the example of the green toad (Bufo Viridis Laurenti, 1768) Describes the morpho-physiological characteristics of the emerging liver in larvae of the green toad (Bufo viridis Laurenti, 1768). Identified that studied the body performs the function of blood during larval development period. In the liver are formed elements of the blood of all lines. Describes he specifics of the organization and morphological changes of the body from developing larvae. There are some pathological changes in the liver and formed elements of blood.

Features of action of weak low-frequency alternating magnetic field on the intensity of division planarian Dugesia tigrina at static magnetic field with "zero" and geomagnetic values It have been shown that exposure of the planarians to low-frequency alternating magnetic field (frequency of 3,7 Hz, the amplitude of 40 nT, exposure 4 h) in combination with a static magnetic field collinear with the induction of 42 mT promoted its division. On other hand compensation of the static magnetic field (induction £ 0,1 mT) by means of alternating magnetic field resulted in the opposite directional inhibitory effect consisted of reduction of the number of divisions of planarians.

The Influence of the Spatial Variability on the Goal-Directed Behavior Organization Serkova V. V., Nikolskaya K. A. The influence of the spatial variability on the goal-directed behavior organization in adult mice line F1 from DBA/2J and C57BL/6J was studied. It has been found that sudden change of initial structure of the maze during the moment of imprinting of spatial information has negatively affected on possibility to form the adaptive behavior in accordance with the offered task conditions. It is assumed that the constancy of the initial spatial information can be an system factor which together with the other will ensure the success of the cognitive process.