03.03.03 Иммунология

The levels of UV-induced mutagenesis change in case of mutations in chromatin-remodeling proteins encoding genes are combined with the rad54 mutation in yeast Saccharomyces cerevisiae Yeast Saccharomyces cerevisiae DOT1, HSM6 and ASF1 genes encode crucial protein chromatin modifiers. We studied the effects of combining dot1, hsm6 and asf1 mutations with rad54 mutation. It’s demonstrated that the enormous increase of UV-induced mutagenesis is representative for dot1rad54, hsm6rad54 and asf1rad54 double mutants. Simultaneously the levels of survival of these double mutants change under the UV light action.

Morphological and physiological parameters of erythrocytes in oxidative stress at different stages of ontogenesis The results indicate the age-related deviations from physiological level of the prevailing number of the investigated morphological and physiological parameters of peripheral erythrocytes functional status, indicating the lack of these indicators stability in the late ontogenesis, significant defects of the gas transmission function of red blood cells, especially presented when inhale rats with hydrogen sulfide gas.  

The effect of Mexidol on clinical and immunological status of patients with chronic obstructive pulmonary disease The assessment of efficiency of meksidol therapy on clinical and immunological status has been made for patients with chronic obstructive pulmonary disease (COPD), the acceptability of physical loads, quality of life and probability of survival of patients with COPD being cousidered against the background of mexidol treatment. It has been established that the use of this preparation in a complex therapy for COPD patients is accompanied by positive dynamics of respiratory symptoms and improves the quality of life of patients. Patients with COPD have a depression of absorbency of neutrophil phagocytics capacity and increasing its metabolic activity with the formation of reactive oxygen species, the probability of a 4 year survival in patients with COPD.  

Research on the influence of endogenous bioregulators, isolated from blood serum and bones of mammals, on the regeneration of amphibian limbs The purpose of this study was to investigate the effect of bioregulators (BR) on anurans limb regeneration and to maintain the viability of the tissues of the developing salamanders regenerate in vitro. During this work it was found that the ability of Xenopus laevis to regenerate hindlimb in metamorphosis stage depends on the level of amputation, while stimulating regeneration by BR isolated from blood serum, decreases when the regenerative capacity increases. BR from serum had a pronounced effect on the regeneration of Xenopus laevis hindlimb in vivo when amputation was in the proximal region. BR from bone and BR from serum had a protective effect on the condition of the tissue regenerated limb of the newt Pleurodeles waltl provided by cultivation in vitro.  

Investigation of thermal resistance and antagonistic properties of the yeast Saccharomyces cerevisiae Using antagonistic properties of some bacteria to inhibit other (pathogenic) has been studied for many years, while little attention was paid to study such properties in yeast. The yeast metabolites and yeast cells action on gram-negative and gram-positive microorganisms was different. Live yeast cells were the most antagonistically active against gram-positive microorganisms and their metabolites - in relation to gram-negative.  

Regularities of formation and erosion processes during spring snowmelt on the territory of agrolandscape and their impact on the quality of river water Analysis of the results four years of research of the snowmelt runoff formation and soil loss on the catchment area of the small river Lubozhikha showed that surface runoff and soil washout has an influence not only on the intensity of erosion processes, but also on the chemical composition of river waters.  

Studying Ontogeny and Ether Oil of N. Velutina Pojark. in Apsheron (Azerbaijan) Mamedova Z. A. In the first year of vegetation of N.velutina Pojark. from section Schizocalyx complete all the stages of ontogeny. Pregeneration of ontogeny is long-term. At the end of the senile state aboveground part of the plant dies off and go into the rest of the month of December. The ether oil has a varied composition: during the growing season dominated lactones, alcohols, ethers, aldehydes. Thus, we have shown in the chemical composition of ether oils from representatives of sections Schizocalyx kind of Nepeta L. Further detailed study of the chemical composition of the ether oils of various types of sections of the genus Nepeta L. can have hemotaksonamic value.

Vocal Variability and Dialectal Forms of Chaffinch Song (Fringilla Coelebs L.) in the Populations of the Central Part of European Russia Astakhova O. A. Questions of evolutionary development of vocalizations (songs, calls) in time and space of many species of birds already for a long time are mentioned in bioacoustics. Connection of geographical variability and structural features of vocalizations was one of the first preconditions of evolutionary hypotheses. Development of song cultures at species of birds with the big repertoires, having social training traditions, remains till now in many respects not clear. In article some features of formation of new song types of chaffinch (Fringilla coelebs L.) and their territorial distribution are considered.

Orchids Rare of Tempertate Zone and Modern Methods of Their Effective Preservation in Artificial Conditions Sheyko E. A. Along with the traditional techniques of plant preservation ex situ biotechnological methods used for these purposes are becoming more and more important. These work investigations dealt with the development and improvement of the methods of isolated rare and disappearing orchid tissue culture in order to apply them in the system of plant resources preservation and procreation. As a result there were obtained callus cultures of generative organs of Himantoglossum caprinum (Bieb.) C. Koch и Ophrys oestrifera M. Bieb. For the first time there was found the interrelation between the callusоgenesis from explants of orchid vegetative and generative organs and ratio of the phytohormonal complex components at the specific stages of the ontogenesis that must be taken into account during the development of methods of these species microclonal reproduction.

The Wood and Ohotpromyslovoe Use of the Baikal Natural Territory: the Aspect Connection of Logging to Hunting Tradeo Leontiev D. F. The interpretation of natural systems as objects of the corresponding of economy impact has executed. The condition of impact on the natural complexes has reflected. The forecast of their changes has given. The impact of logging on volumes of booty of hunting products has shown.

Diurnal Rhythm of Caloric Equivalent of the Body Mass Loss in the Coal Tit (Parus ater, Aves) in the Autumn-Winter Period Gavrilov V. V. Caloric equivalent of the body mass loss in the Coal Tit (Parus ater, Aves) in the autumn-winter period had a well pronounced diurnal rhythm with minimal values in the morning and maximum at night. The differences between minimum and maximum values of caloric equivalent of the body mass loss was 240%. Diurnal rhythm of caloric equivalent of the body mass loss had differences from the rhythms of other energetic characteristics and equal to the rhythm of the locomotor activity of Coal Tits.

The Morphometric Characteristic of the Wood Plants Growing in the Conditions of Impact of Vehicle Emissions Kolmogorova E. Y. It is established, that the pollution of crossroads by emissions of motor transport causes the deterioration of the morphometric characteristics of the studied plants. A more significant decrease in studied indicators was observed in plants growing near intersections, characterized by a high rate of the complex indicator. It is proved, that one of the reasons of reduction of morphometric characteristics of the studied plants and deterioration of their living conditions is the quantitative and qualitative composition of pollutant emissions from the road traffic.

The Assesment of the Cytokine Profile and the Enzymatic Activity of Gingival Crevicular Fluid at the Residents of Volgograd With Intact Perio-Dontium and in Patients With Mild Periodontitis Patrusheva M. S., Mikhalchenko v. F., Yakovlev A. T. The inclusion of biochemical and immunological analysis of gingival crevicular fluid in the complex examination of patients with periodontitis allows to increase the efficiency of the diagnosis and treatment of this disease. It is shown, that already in the early stages, periodontal disease are accompanied by considerable disorders of metabolism and local immune response, preceding clinical implications.

Intercommunication of Disbakteriosis and Allergic Diseases Parakhonsky A. P. The modern state of amicrobiocenosis intestines problem from the point of evidence — based medicine and interrelation of dysbacteriosis and allergic diseases is characterized. The important role of physiological micro flora and immune system interaction is shown. The attempt to estimate the influence of dysbacteriosis and intestine parasites on allergic diseases is made; mechanisms of modulation with the help probiotics on an allergic inflammation are described.

The Influence of Industrial Pollution on the Photosynthesis Of Some Trees Rakhimov T. U. In the article the pollution being emitted to the atmosphere by the industrial plants, which recycle gas and its affect to the photosynthesis indicator of fruitful and fruitless trees have been studied. According to the obtained information, in the level of activeness of fruitful trees they are as follows: quince> apple> almond, among planted trees they are located in the following location: mulberry> pine tree> willow> poplar> maple tree.

Effect of Mesorelif on Water and Physical Properties of Gray Forest Soils of Birch-Aspen Forest Reihert E. V., Ni E. U. The article examines the impact of meso-relief on the physical and water-physical properties of gray forest soils in birch-aspen forest on the slopes of the example of the northern and southern exposure. During the studies it was found that depending on the element of relief structural changes of the aggregate, the field moisture content, density and temperature of gray forest soils.

Some Features of the Effect of Ultrasound on Microorganisms Antusheva T. I. The article presents a review of current scientific and methodical literature characterizing the effects of ultrasound on biological objects. The mechanisms and some of the features of the influence of physical factors on microorganisms are described. The different biological effects occurring in bacteria under the influence of ultrasonic fields of different intensity and frequency are considered. The examples and prospects of practical application of ultrasonic technology in microbiology are given.

Astragalus Ponticus Pall. — Rare View of the Flora in Eastern Europe: Chorology Features and Ecologo-Cenotic Confinement Kucherevsky V. V., Baranets N. A., Sirenko T. V., Shol G. N., Demina O. N., Rogal L. L. The paper provides information on the results of the chorologic research A. ponticus in Eastern Europe: Moldova, Pridnestrovie, Russia, Ukraine. It is pointed out of characteristics of distribution of the species as a whole and in individual regions. Shown ecologo-cenotic confinement in different parts of the area.

Bioecological Features of Some Species Genus of Rhamnus L. in Arboretum NAS of Azerbaijan Abbasova Z. G. In the article is given data with seed propagate, features development and rhythm growth of species Rhamnus alaternus and Rh. dahurica. It was noted time flowering of one flower, inflorescence of the plants. In conditions of Apsheron these plant well growth and fructify. These species hot-forst resistance. Their may be use in landscape design, single, groups, fence and greenery.